Chiral Cobalt‐Salen Complexes: Ubiquitous Species in Asymmetric Catalysis

Chiral poly-rare earth metal complexes in asymmetric catalysis

Asymmetric catalysis is a powerful component of modern synthetic organic chemistry. To further broaden the scope and utility of asymmetric catalysis, new basic concepts for the design of asymmetric catalysts are crucial. Because most chemical reactions involve bond-formation between two substrates or moieties, high enantioselectivity and catalyst activity should be realized if an asymmetric cat...

Chiral allene-containing phosphines in asymmetric catalysis.

We demonstrate that allenes, chiral 1,2-dienes, appended with basic functionality can serve as ligands for transition metals. We describe an allene-containing bisphosphine that, when coordinated to Rh(I), promotes the asymmetric addition of arylboronic acids to α-keto esters with high enantioselectivity. Solution and solid-state structural analysis reveals that one olefin of the allene can coor...

Asymmetric Catalysis by Chiral Rhodium Complexes in Hydrogenation and Hydrosilylation Reactions

The preparation of optically active molecules needs a chiral auxiliary. It is important to use the minimum amount of this auxiliary, and from that point of view asymmetric catalysis is much more advantageous than stoichiometric asymmetric synthesis. Some homogeneous catalysts prepared from chiral complexes have become during the past few years a useful tool in asymmetric synthesis. The complexe...

Chiral olefin ligands-new "spectators" in asymmetric catalysis.

Ion-paired chiral ligands for asymmetric palladium catalysis.

Conventional chiral ligands rely on the use of a covalently constructed, single chiral molecule embedded with coordinative functional groups. Here, we report a new strategy for the design of a chiral ligand for asymmetric transition-metal catalysis; our approach is based on the development of an achiral cationic ammonium-phosphine hybrid ligand paired with a chiral binaphtholate anion. This ion...